5-hydroxy-3-methylglutaryl-coenzyme A reductase

noun
a liver enzyme that is responsible for producing cholesterol
Syn: ↑HMG-CoA reductase
Hypernyms: ↑reductase

Useful english dictionary. 2012.

Look at other dictionaries:

  • 3-hydroxy-3-méthylglutaryl-coenzyme A — Structure de la 3 hydroxy 3 méthylglutaryl coenzyme A Général Synonymes …   Wikipédia en Français

  • β-hydroxy-β-methylglutaryl-CoA — A key intermediate in the synthesis of ketone bodies, of steroids, and of farnesyl and geranyl derivatives. SYN: 3 hydroxy 3 methylglutaryl CoA. β hydroxy β methylglutaryl lyase an enzyme, found primarily in liver and rumen epithelium that… …   Medical dictionary

  • reductase — noun an enzyme that catalyses the biochemical reduction of some specified substance • Hypernyms: ↑enzyme • Hyponyms: ↑HMG CoA reductase, ↑5 hydroxy 3 methylglutaryl coenzyme A reductase …   Useful english dictionary

  • Hydroxymethylglutaryl-CoA reductase (NADPH) — In enzymology, a hydroxymethylglutaryl CoA reductase (NADPH) (EC number|1.1.1.34) is an enzyme that catalyzes the chemical reaction:(R) mevalonate + CoA + 2 NADP+ ightleftharpoons (S) 3 hydroxy 3 methylglutaryl CoA + 2 NADPH + 2 H+The 3… …   Wikipedia

  • Dephospho-(reductase kinase) kinase — dephospho [reductase kinase] kinase Identifiers EC number 2.7.11.3 CAS number 72060 33 4 …   Wikipedia

  • HMG-CoA reductase — protein Name = 3 hydroxy 3 methylglutaryl Coenzyme A reductase caption = HMG CoA reductase width = 200 HGNCid = 5006 Symbol = HMGCR AltSymbols = EntrezGene = 3156 OMIM = 142910 RefSeq = NM 000859 UniProt = P04035 PDB = ECnumber = 1.1.1.88… …   Wikipedia

  • HMG-CoA reductase — noun a liver enzyme that is responsible for producing cholesterol • Syn: ↑5 hydroxy 3 methylglutaryl coenzyme A reductase • Hypernyms: ↑reductase …   Useful english dictionary

  • HMGCR — 3 hydroxy 3 methylglutaryl Coenzyme A reductase, also known as HMGCR, is a human gene. PBB Summary section title = summary text = HMG CoA reductase is the rate limiting enzyme for cholesterol synthesis and is regulated via a negative feedback… …   Wikipedia

  • HMG-CoA-Reduktase — Stäbchenmodell des Dimers mit Kalotten: Coenzym A (blau), β Hydroxy β methyl glutarylsäure (rot) und NADP (gr …   Deutsch Wikipedia

  • Statin development — The discovery of HMG CoA (3 hydroxy 3 methylglutaryl CoA) reductase inhibitors, called statins, was a breakthrough in the prevention of hypercholesterolemia and related diseases. Hypercholesterolemia is considered to be one of the major risk… …   Wikipedia

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